Anyone who has known a child born with a congenital disorder, paralyzed in an acciden, or challenged by a complex medical condition, knows that hope and healing are inseparable. The dream that scientific breakthroughs will give doctors the tools and medicines needed to cure disease is a real one. At Shriners Hospitals for Children Medical Center — Lexington, our doctors and researchers work collaboratively to find new ways to heal children with complex medical needs.
We do not know precisely when the answers to these and other questions will come, but we can rest assured that the research taking place today will positively impact the lives of children for generations to come.
Engaged in a quest to improve treatments and outcomes for the children we treat, researchers at Shriners Hospitals for Children Medical Center — Lexington are currently working on the following projects:
- Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet
- Bracing in Adolescent Idiopathic Scoliosis Trial II: Observational Follow-up of BrAIST I Cohort (BrAIST II)
- Involved and Uninvolved Changes in Post-operative Unilateral Pediatric Elbow Fracture
- Duration of Brace Wear in Clubfoot Treatment — A Prospective Randomized Trial
- Identification of Genetic Susceptibility in Adolescent Idiopathic Scoliosis
- Long-term Follow-up of Individuals with CP who Underwent Gait Analyses
- Oxygen Consumption and Pulmonary Function in Adolescent Idiopathic Scoliosis Patients Pre- and Post- Surgical Intervention
- Gait Symmetry in Children and Adolescents with Unilateral Lower Extremity Amputations
Presentations and publications
Our researchers frequently present findings at professional conferences such as the:
Our researchers have also produced over 100 publications that have appeared in a variety of scientific medical journals, including Journal of Pediatric Orthopaedics, Developmental Medicine and Child Neurology, and Clinical Rehabilitation. Following is a list of recent publications.
- Riley, SA, Burgess, RC. Hypoplasia, Brachydactyly, and Other Failures of Formation. Chapter 10 in The Pediatric Upper Extremity. Springer Reference: 213-236, 2015.
- Davids, Oeffinger, Bagley, Sison-Williamson, Gorton. Relationship of Strength, Weight, Age, and Function in Ambulatory Children with Cerebral Palsy. Journal of Pediatric Orthopaedics, 35(5): 523-529.
- White, H. All in the hope of saving a few minutes. Commentary to original article by Avery et al. Developmental Medicine and Child Neurology. 55(6), 492.
- Clark, Puleo, Milbrandt, Hilt. Retention of insulin-like growth factor I bioactivity during fabricatino of sintered polymeric scaffolds. Biomedical Materials, 9 (2014) 025015.
- Hawkins, Milbrandt, Puleo, Hilt. Composite Hydrogel Scaffolds with Controlled Pore Opening via Biodegradable Hydrogel Porogen Degradation. Journal of Biomedical Materials, 102(2): 400-412.
- Hassani, Krzak, Johnson, Flanagan, Gorton, Bagley, Ounpuu, Romness, Tylkowski, Oeffinger. One Minute Walk Test and Timed Up & Go in Children with Cerebral Palsy: Performance and Minimum Clinically Important Differences. Developmental Medicine and Child Neurology. 56(5), 482-487.
- Milbrandt, Hilt, Clark, Puleo. Tailoring Properties of Microsphere-Bsed Poly(lactic-co-glycolytic acid) Scaffolds. Journal of Biomedical Materials Research: Part A. 102(2), 348-357.
- Oeffinger, Gurka, Hassani, Kuperminc. Accuracy of Skinfold and Bioelectrical Impedance Assessments of Body Fat Percentage in Ambulatory Individuals with Cerebral Palsy. Developmental Medicine and Child Neurology. 56(5), 475-481.
- Kelly, Heyworth, Kruse, Edmonds, VanderHave, Podeszwa, Talwalkar, Warner, Gordon. Current State of Pediatric Orthopaedic Disaster Response. Journal of Pediatric Orthopaedics. 34(3), 231-238.
- Clark, Milbrandt, Hilt, Puleo. Mechanical Properties and Dual Drug Delivery Application of Poly(lactic-co-glycolic acid) scaffolds fabricaed with a poly(β-amino ester) porogen. Acta Biomaterialia. 10(2014), 2125-2132.
- Hosseinzadeh, Milbrandt. Congenital Clubfoot. JBJS Reviews. 2(3), e3.
- Riley SA, Burgess RC. Pediatric Upper Extremity Disorders. Chapter 59 in Orthopaedic Knowledge Update 11 publication: AAOS 2014.
- Morgenstein, Davis, Talwalkar, Iwinski, Walker, Milbrandt. A Randomized Clinical Trial Comparing Reported and Measured Wear-rates in Clubfoot Bracing Using a Novel Pressure Sensor. Journal of Pediatric Orthopaedics, 01241398-900000000-99812.
- Oeffinger, Gorton, Hassani, Sison-Williamson, Johnson, Whitmer,Romness, Kryscio, Tylkowski, Bagley. Variability explained by strength, body composition and gait impairment in activity and participation measures for children with cerebral palsy: a multicenter study. Clinical Rehabilitation, 28(10): 1053-1063.
- Alexander, Horstmann, Milbrandt. Transportation of Pediatric Femur Fractures to a Tertiary Care Center, a Retrospective Review. Iowa Orthopaedic Journal, 2014, 34:166-170.
- Thompson, Hosseinzadeh, Muchow, Talwalkar, Iwinski, Walker, Milbrandt. Syringomyelia and vertebral osteochondromas in patients with multiple hereditary exostosis. Journal of Pediatric Orthopaedics Part B. 23(5): 449-453.
- Fisher, Palomino, Milbrandt, Hilt, Puleo. Improved small molecule drug release from in situ forming poly(lactic-co-glycolic acid) scaffolds incorporating poly(β-amino ester) and hydroxyapatite microparticles. Journal of Biomaterials Science, Polymer Edition. 25(11): 1174-1193.