Skip to navigation

Masao Kaneki, M.D., Ph.D.

Masao Kaneki, M.D., Ph.D.

Masao Kaneki, M.D., Ph.D., is a scientific investigator at Shriners Hospitals for Children — Boston and an associate professor in the department of anesthesia at Massachusetts General Hospital and Harvard Medical School.

Dr. Kaneki is the director of the Signal Transduction Laboratory at Massachusetts General Hospital. His major research efforts have been focused on burn injury-induced metabolic alterations, including hyperlactatemia, hypermetabolism, muscle wasting, mitochondrial dysfunction and insulin resistance, in mice. His research team has shown that farnesyltransferase inhibitor prevents burn injury-induced metabolic derangements in mice.

Dr. Kaneki’s team has found that supplementation with reduced form of coenzyme Q10 (ubiquinol) ameliorated burn injury-induced metabolic derangements in mice. Based on the preclinical data in mice, the team has been conducting a clinical trial of coenzyme Q10 (ubiquinol) in adult burn patients. Dr. Kaneki actively collaborates with many investigators at Shriners Hospitals for Children — Boston, including J.A. Jeevendra Martyn, M.D., Yong-Ming Yu, M.D., Ph.D., and Shingo Yasuhara, M.D., Ph.D.

Dr. Kaneki has had over 80 journal articles published in top tier journals such as Science Signaling, J Biol Chem and Diabetes. He has presented over 100 abstracts and is an ad hoc member of NIH Study Section (SAT, CADO).

Dr. Kaneki is on the editorial board of numerous journals including: Shock, Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches; Metabolism, Clinical and Experimental; and Journal of Burn Care & Research.

Current positions:

  • Scientific Investigator, Shriners Hospitals for Children — Boston
  • Associate Professor, Dept. of Anesthesia, Massachusetts General Hospital
  • Associate Professor, Dept. of Anesthesia, Harvard Medical School

Education/training:

  • BS, Biology, The University of Tokyo, Japan
  • M.D., The University of Tokyo
  • Ph.D., The University of Tokyo

Scholarly activities: