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Medical research

Medical research

Medical research

Shriners Hospitals for Children — Chicago specializes in research in orthopaedics, spinal cord injury, rehabilitation and craniofacial and plastic surgeries. We have been successful in procuring extramural funding from multiple sources, including the National Institutes of Health, National Institute on Disability, Independent Living and Rehabilitation Research, the Department of Defense, the Falk Foundation, other philanthropic and industrial sources, and internal competitive research funding through Shriners Hospitals for Children nationally.

The research team at the Chicago Shriners Hospital publishes regularly on topics covering different pediatric pathologies. Below are some recent publications from the research team.

Manuscripts/publications

  • Ackman J: Surgical Technique: Resection Arthroplasty. Hip Arthroscopy and Hip Joint Preservation Surgery, Springer New York, 41: 549-553, October, 2014
  • Albert, C., Jameson, J., Smith, P. and Harris, G.: Reduced Diaphyseal Strength Associated with High Intracortical Vascular Porosity within Long Bones of Children with Osteogenesis Imperfecta. Bone. 66:121–130, 2014. doi:10.1016/j.bone.2014.05.022
  • Anissipour AK, Hammerberg KW, Caudill A2, Kostiuk T, Tarima S, Zhao HS, Krzak JJ, Smith PA. Behavior of scoliosis during growth in children with osteogenesis imperfecta. J Bone Joint Surg Am. 2014 Feb 5;96(3):237-43. doi: 10.2106/JBJS.L.01596.
  • Bandini L, Danielson M, Esposito LE, Foley JT, Fox MH, Frey GC, Fleming RK, Krahn G, Must A, Porretta DL, Rimmer J, Rodgers AB, Stanish H, Urv T, Vogel LC, Humphries K. Obesity in Children with Developmental and/or Physical Disabilities.  Disability and Health. 2015; 8(3):309-316. Doi: 10:1016/j.dhjo.2015.04.005.
  • Cradock MM, Gray KE, Kapp-Simon KA, Collett BR, Buono LA, Speltz ML.  Sex differences in the neurodevelopment of school-aged children with and without single-suture craniosynostosis. Child’s Nervous System, 2015: 31:1103-1111
  • Collett BR, Kapp-Simon KA, Wallace E, Cradock MM, Speltz ML: Attention and executive function in children with and without single-suture craniosynostosis. Child Neuropsychol, in press
  • Gray KE, Kapp-Simon KA, Starr JR, Collett BR, Wallace ER, Speltz ML. Predicting developmental delay in a longitudinal cohort of preschool children with single-suture craniosynostosis: is neurobehavioral assessment important? Dev Med Child Neurol. 2015;May;57(5):456-62.doi:10.1111/dmcn.12643.
  • Gray KE, Cradock MM, Kapp-Simon KA, Collett BR, Speltz ML. Longitudinal analysis of parenting stress in mothers and fathers of infants with and without single-suture craniosynostosis.  Cleft Palate-Craniofacial Journal. 2015 Jan;52(1):3-11. doi: 10.1597/13-239.
  • Gussous, Y.M., Tarima, S., Zhao, S., Khan, S., Caudill, A., Sturm, P., Hammerberg, K.W. Serial Derotational Casting in Idiopathic and Non-Idiopathic Progressive Early Onset Scoliosis.  Spine Deformity, 3:233-238, 2015
  • Hassani S, Krzak JJ, Johnson B, Flanagan A, Gorton G 3rd, Bagley A, Ounpuu S, Romness M, Tylkowski C, Oeffinger D. One-Minute Walk and Modified Timed Up and Go Tests in children with cerebral palsy: performance and minimum clinically important differences. Dev Med Child Neurol. 2014 May;56(5):482-9. PubMed PMID: 24843890.
  • Holbein, C., Zebracki, K., & Holmbeck, G. (2014). Development and validation of the Peer Interaction Macro-coding System scales (PIMS): A new tool for observational measurement of social competence in youth with spina bifida.
  • Holbein, C. E., Lennon, J. M., Kolbuck, V. D., Zebracki, K., Roache, C., & Holmbeck, G. N. (2015). Observed differences in social behaviors exhibited in peer interactions between youth with spina bifida and their peers: Neuropsychological correlates. Journal of Pediatric Psychology. 40(3), 320-335. doi: 10.1093/jpepsy/jsu101.
  • Hwang, M., Zebracki, K., Chlan, K., & Vogel, L. (2014). Longitudinal employment outcomes in adults with pediatric-onset spinal cord injury. Spinal Cord, 52(6), 477-482. doi: 10.1038/sc.2014.32
  • Hwang, M., Zebracki, K., Vogel, L.. Occupational characteristics of adults with pediatric-onset spinal cord injury. Top Spinal Cord Inj Rehabil. 2015; 21:10-19. doi: 10.1310/sci2101-10.
  • Hwang, M., Zebracki, K., & Vogel, L. (in press). Medication profile and polypharmacy in adults with pediatric-onset spinal cord injury. Spinal Cord. doi: 10.1038/sc.2015.62
  • January, A.M, Zebracki, K., Czworniak, A., Chlan, K., & Vogel, L. (2015). Predictive factors of hospitalization in adults with pediatric-onset SCI: A longitudinal analysis. Spinal Cord, 53(4), 314-319. doi: 10.1038/sc.2015.13
  • January, A.M, Zebracki, K., Chlan, K., & Vogel, L. (2015). Understanding post-traumatic growth following pediatric-onset spinal cord injury: The critical role of coping strategies for facilitating resiliency. Developmental Medicine & Child Neurology. Advance online publication. doi: 10.1111/dmcn.12820
  • January AM., Zebracki, K., Chlan, K., Vogel, L. Mental health and risk of secondary medical complications in adults with pediatric-onset spinal cord injury. Top Spinal Cord Inj Rehabil. 2014; 20:1-12. doi 10.1310/SCI2001-1.
  • Kapp-Simon KA, Edwards T, Ruta C, Crilly Bellucci C, Topolski TD, Rumsey NJ, Patrick DL. Shared surgical decision-making and youth resilience: Correlates of satisfaction with clinical outcomes. Journal of Craniofacial Surgery, in press.
  • Kelly, E. H., & Vogel, L. C. (2013). An overview of psychosocial health among youth with spinal cord injury. Topics in Spinal Cord Injury Rehabilitation, 19(2), 129-141. doi: 10.1310/sci1902-129
  • Kelly E, Riordan AL, Zebracki K, Thorpe S, Vogel LC . Relationships between caregiver characteristics and health-related quality of life among youths with spinal cord injury. Top Spinal Cord Inj Rehabil. (in press).
  • Klaas SJ, Kelly EH, Anderson CJ, Vogel LC. Depression and anxiety in adolescents with pediatric-onset spinal cord injury. Top Spinal Cord Inj Rehabil. 2014; 20:13-22. doi 10.1310/SCI2001-13.
  • Krzak, J., Corocs, D., Damiano, D., Graf, A., Hedeker, D., Smith, P., and Harris, G.: Kinematic Foot Types in Youth with Equinovarus Secondary to Hemiplegia. Gait and Posture. 41(2):402-408, 2015.
    doi: 10.1016/j.gaitpost.2014.10.027
  • Kowalewicz EA, Ausikaitis AE, Kapp-Simon KA.  Children with Diagnoses of Cleft Lip and/or Palate: What School Psychologists Need to Know. School Psychology Forum, in press.
  • Mulcahey MJ, Calhoun CL, Sinko R, Kelly EH, Vogel LC. The Spinal Cord Independence Measure (SCIM)-III Self Report for Youth. Spinal Cord. doi:10.1038/sc.2015.103
  • Patel RM, Nagamani SC, Cuthbertson D, Campeau PM, Krischer JP, Shapiro JR, Steiner RD, Smith PA, Bober MB, Byers PH, Pepin M, Durigova M, Glorieux FH, Rauch F, Lee BH, Hart T, Sutton VR. A cross-sectional multicenter study of osteogenesis imperfecta in North America - results from the linked clinical research centers. Clin Genet. 2015 Feb;87(2):133-40. doi: 10.1111/cge.12409. Epub 2014 May 30. PubMed PMID: 24754836
  • Riordan A, Kelly EH, Mulcahey MJ, Betz RR, Vogel LC Psychosocial outcomes among youth with spinal cord injury by neurological impairment. J Spinal Cord Med 2015; 38:76-83. doi: 10.1179/2045772313Y.0000000162.
  • Russell, H.R., January, A. M.,  Kelly, E.H.,  Mulcahey, M.J. Betz, R.R. & Vogel, L.C. Patterns of Coping Strategy Use and Relationships with Psychosocial Outcomes in Adolescents with Spinal Cord Injury. Journal of Pediatric Psychology. 2015;40(5):535-543.DOI: 10.1093/jpepsy/jsu159.
  • Saunders LL, Selassie A, Cao Y, Zebracki K, Vogel LC. Epidemiology of pediatric traumatic spinal cord injury in a population-based cohort. Top Spinal Cord Inj Rehabil. (in press).
  • Schnorenberg AJ, Slavens BA, Wang M, Vogel LC, Smith PA, Harris GF. Biomechanical model for evaluation of pediatric upper extremity joint dynamics during wheelchair mobility. J Biomechanics 2014; 47:269-276. DOI10.1016/j.jbiomech2013.11.014.
  • Slavens, B.A., Schnorenberg, A.J., Aurit, C.M., Graf, A., Krzak, J., Reiners, K., Vogel, L.C. and Harris, G.: Evaluation of Pediatric Manual Wheelchair Mobility using Advanced Biomechanical Methods. BioMed Research International: Special Issue on Wheeled Mobility, Volume 2015, Article ID 634768, 11pgs., 2015. doi: 10.1155/2015/634768
  • Slavin M, Mulcahey MJ, Vogel L, Calhoun C, Jette A. Development and validation of short forms of activity for youth with SCI. Spinal Cord, In Press.
  • Smith PA, Kuo KN, Graf AN, Krzak J, Flanagan A, Hassani S, Caudill AK, Deitz FR, Morcuende J, Harris GF Long-term Results of Comprehensive Clubfoot Release Versus the Ponseti Method: Which is Better?. Clin Relat Res. 2014; 472:1281-1290.
  • Speltz ML, Collett BR, Wallace ER, Starr JR, Cradock MM, Buono L, Cunninham M, Kapp-Simon KA, Pediatrics, 135(3) March 2015 Mar;135(3):e615-23. doi: 10.1542/peds.2014-1634.
  • Vogel LC, Zebracki K. Long-Term Outcomes of Pediatric-Onset Spinal Cord Injuries: Implications for Life Care Planning. Journal of Life Care Planning. (in press) 2015.
  • Wheeldon G, Altiok H. Dysplasia epiphysealis hemimelica of the knee: an unusual presentation with intra-articular loose bodies and literature review. J Pediatr Orthop B. 2015 Jul;24(4):326-9. doi: 10.1097/BPB.0000000000000150.
  • Wingo BC, Mehta TS, Qu P, Vogel LC, Rimmer JH. Exploratory study examining clinical measures of adiposity risk for predicting obesity in adolescents with physical disabilities. Am J Phys Med Rehabil. 2015; 94(8): 585-594. Doi ; 10.1097/PHM.0000000000000323.
  • Zebracki K, Chlan K, Vogel LC. Long-Term Outcomes of Pediatric-Onset Spinal Cord Injury. (2014). In Vogel LC, Zebracki K, Betz RR, Mulcahey MJ (Eds.), Spinal Cord Injury in the Child and Young Adult. Mac Keith Press, London, UK. p 359-375.
  • Zebracki, K., Thawrani, D., Oswald, T., Anadio, J., Sturm, P., & Spine Deformity Study Group (2013). Predictors of emotional functioning in youth after surgical correction of idiopathic scoliosis. Journal of Pediatric Orthopaedics, 33(6), 624-627. doi: 10.1097/BPO.0b013e318288b77f

Books

  • Vogel LC, Zebracki K, Betz RR, Mulcahey MJ (Eds.), Spinal Cord Injury in the Child and Young Adult. Mac Keith Press, London., UK. 2014.
  • Section Editor of Section V11. Special Considerations and Editorial Team. Chhabra HS (Ed.), ISCoS Textbook on Comprehensive Management of Spinal Cord Injuries. Wolters Kluwer, (India) Pvt. Ltd., New Delhi. 2015.
  • Bosques G, Vogel LC. Medical Complications and Management. (2014). In Vogel LC,  Zebracki K, Betz RR, Mulcahey MJ eds. Spinal Cord Injury in the Child and Young Adult. Mac Keith Press, London, UK.
   
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