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Amniotic band syndrome

Amniotic band syndrome

Amniotic band syndrome

Amniotic band syndrome (ABS) occurs when the fetus is entangled with strands of amniotic bands that are fibrous and string like. These strands in the womb restrict blood flow, affecting the baby’s growth and development, and can cause deformities to the arms, face, fingers, legs and toes.

In some cases, a fibrous band can be so tightly wrapped around a baby’s limb that the limb may need to be amputated. Some newborns can have a cleft palate if the bands are across their face, or clubfoot if the bands wrap around the feet.

ABS is caused by damage to a section of the placenta known as the amnion. The placenta is the baby’s source for blood while they are growing in their mother’s womb. ABS is not genetic, nor is it a result of anything the mother did or did not do during pregnancy.

Signs of amniotic band syndrome

The types of deformities vary depending on which area of the body the band has restricted blood flow to. Symptoms of ABS may include:

  • An abnormal gap in the newborn’s face, known as a cleft if it goes across the face
  • Congenital amputation – a section or an entire limb missing
  • Physical defects in the abdomen or chest wall
  • A permanent band or indentation mark on the baby’s arm, finger, leg or toe

Diagnosing amniotic band syndrome

Because ABS occurs in the womb and the defects are visible, your doctor is able to diagnose ABS when your child is born.

Evaluation and treatment of amniotic band syndrome

Shriners Hospitals for Children offers treatment for ABS that is based upon the severity of the deformities. In some cases, your child’s deformity may not be severe and treatment may not be needed. Children with some physical defects or limb deficiencies may receive physical and occupational therapy to support their growth and development.

In cases where amniotic band syndrome has affected a limb, children may be able to receive a prosthesis. These devices can begin to be used when children are very young, typically when they are neurodevelopmentally ready to begin standing and walking (usually between 12 and 18 months of age). Occasionally, surgery will be needed to optimize the site where the prosthesis will be attached.