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Shriners Hospitals for Children — Greenville visitor information.

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Specialty clinics

Specialty clinics


About one in 20 children are born with a genetic condition. For this reason, Shriners Hospitals for Children — Greenville has partnered with Greenwood Genetics Center to provide a once-a-month comprehensive genetics clinic. The goals of this clinic are to diagnose and treat children with genetic conditions, as well as to provide the family with the information and guidance they will need for the management of their child’s condition. Information gained from a genetic evaluation may also help to determine the underlying cause of a child’s problem in addition to determining what the parents may expect for future siblings.


Shriners Hospitals for Children — Greenville provides a rheumatology clinic to address the needs of children with juvenile idiopathic arthritis (JIA). Appropriate children for referral to this clinic include children with unexplained joint swelling and/or a positive blood test for JIA. Children with auto-immune disorders that do not involve the joints do not meet the criteria for this clinic.

Tone management

Shriners Hospitals for Children — Greenville’s tone management clinic is comprised of a multidisciplinary team consisting of five physicians with specialized training in pediatric orthopaedics, neurosurgery, neurology, physiatry and genetics. Occupational therapists, physical therapists, social workers, registered nurses, physician assistants, nurse practitioners, motion analysis center representatives and an intrathecal Baclofen therapy specialist support the physicians. The treatment plans that are developed in this very comprehensive clinic are individualized for each patient’s special needs. Examples of these plans of care can include recommendations for oral baclofen, baclofen trials to determine appropriateness of a Baclofen pump placement, Botulinum toxin A injections, orthopaedic surgery, stretch casting and physical and occupational therapies.

Rett syndrome

Presenting in infancy or early childhood, Rett syndrome is a rare neurological disorder that can affect many aspects of a child’s life, including the ability to walk, eat, speak, learn and breathe. While babies with Rett syndrome typically develop normally for the first six to 18 months, symptoms can then appear slowly or rapidly.

Caused by a gene mutation and occurring almost solely in females, the complex condition requires many specialists to play a part in the care of the child. A multidisciplinary team, comprised of an orthopaedic surgeon, behavioral pediatrician, neurologist, geneticist, nutritionist and physical and occupational therapists, work together to create the best treatment plan for each individual. At the Greenville Shriners Hospital’s bi-monthly Rett syndrome clinic, patients are evaluated on an on-going basis.

Arthrogryposis multiplex congenita

Arthrogryposis multiplex congenita (AMC) is characterized by multiple joint contractures (stiff joints), which can include weakness, fibrosis and associated lack of muscular development. Treatment may include physical and occupational therapy, splints or casts. Surgery may be necessary to improve joint function for children born with this rare, non-progressive, congenital disorder.

The Greenville Shriners Hospital provides world-class expertise in the evaluation and treatment of children with AMC. A multidisciplinary team of neurologists, geneticists, physical and occupational therapists and pediatric orthopaedic surgeons work together to achieve non-operative and operative management of the condition.

The goals of management include improving range of motion, achieving ambulation and promoting independence in life’s daily activities. The upper and lower extremity teams work in concert to achieve these goals and coordinate care to maximize the child’s potential.