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News Thursday, May 18, 2017

New facility dedicated to pediatric musculoskeletal research opens

Lab will focus on regenerative medicine

On Wednesday, May 17, 2017, Shriners Hospitals for Children — St. Louis officially opened its new research lab that focuses on regenerative medicine and is already gaining international recognition. It is the premier site for pediatric musculoskeletal research.

Last year, the Shriners Hospitals’ research team lead by Farshid Guilak, Ph.D., created a living tissue hip joint replacement for patients currently receiving synthetic replacement joints that eventually wear out. This advancement is key for children who need replacement joints since a living joint could grow with the child. SMART cell technology is also being combined with this discovery to grow a living joint with these same disease-fighting properties.

Last week, it was announced that by using a new gene-editing technology, they have re-wired living cells to produce their own targeted arthritis-fighting vaccine. These SMART (stem cells modified for autonomous regenerative therapy) cells could offer more targeted treatment options for children and adults with inflammatory and chronic conditions.

Learn more about the new research facility at Shriners Hospitals for Children — St. Louis by viewing the story on

Staff in the new research facility.