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St. Louis Shriners Hospital awarded $1.68 million grant for research

The newly established Clinical Research Infrastructure Core will help streamline clinical research

In late 2017, Shriners Hospitals for Children — St. Louis was awarded a $1.68 million grant to build the infrastructure for a comprehensive clinical research program at the hospital. Michael Whyte, M.D., and Charles Goldfarb, M.D., jointly applied for a Special Shared Facilities Grant through Shriners Hospitals for Children, to create the Clinical Research Infrastructure Core (CRIC), a team of four specialized professionals dedicated to providing core support for physicians and other staff wanting to conduct clinical research. Drs. Whyte and Goldfarb will co-direct the CRIC. Services provided by the CRIC will include completion of regulatory requirements, assistance designing and implementing research studies, finding funding sources for projects, enrolling participants in studies, creating research databases and data collection systems, and providing sound scientific support in analyzing study data.

In 2017, Shriners Hospitals for Children funded 22 special shared facilities grants throughout the hospital system. The grants are contingent on sharing resources with other Shriners Hospitals locations and sometimes even other research facilities. Anyone in the hospital can utilize the CRIC for research support.

The CRIC team consists of:

  • A clinical research coordinator who works with clinical investigators to support, facilitate and coordinate clinical research activities
  • A senior clinical research coordinator who independently coordinates and is accountable for the overall administration and outcome of multiple clinical studies
  • A clinical scientist who provides a variety of technical and scientific support required for the clinical research process
  • A clinical research manager who will lead the CRIC team, help secure the operational and fiscal integrity of hospital’s research program, provide regulatory oversight, and direct supervision of the clinical research staff

The CRIC hopes to maximize the research efforts of everyone at the St. Louis Shrines Hospital, from orthopaedic to metabolic to rehabilitation and beyond, and also enhance collaborative efforts across the Shriners Hospitals for Children system. Such collaborations lead to better quality research and better outcomes for patients.

“Our mission is to conduct the highest quality research, emphasizing safety and benefit to our patients and humanity,” says Amy Reeves, CRIC clinical research manager.

This is the second Special Shared Facilities Grant that Shriners Hospitals for Children — St. Louis has received. The first grant, awarded in 2016, established a core unit to run the XTremeCT II, a cutting-edge, high resolution peripheral quantitative computed tomography machine, designed to visualize and quantify the three-dimensional microarchitecture of the bone. This type of scan can provide more and better data on the quality of bone.

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